Spatial frequency content in optical mapping of cardiac cell monolayers.

Vetter Harold Bien , Emilia Entcheva , Arkady Pertsov , Sergey Mironov and Frederick Cardiac Cell Monolayers Spatial Frequency Content in Optical Mapping

Letters to the Editor Spatial Frequency Content in Optical Mapping of Cardiac Cell Monolayers

Mironov, Sergey F., Frederick J. Vetter, and Arkady M. Pertsov. Fluorescence imaging of cardiac propagation: spectral properties and filtering of optical action potentials. Am J Physiol Heart Circ Physiol 291: H327–H335, 2006.—Fluorescence imaging using voltage-sensitive dyes is an important tool for studying electrical propagation in the heart. Yet, the low amplitude of the voltage-sensitive c...

Entropy Rate Maps of Complex Excitable Dynamics in Cardiac Monolayers

The characterization of spatiotemporal complexity remains a challenging task. This holds in particular for the analysis of data from fluorescence imaging (optical mapping), which allows for the measurement of membrane potential and intracellular calcium at high spatial and temporal resolutions and, therefore, allows for an investigation of cardiac dynamics. Dominant frequency maps and the analy...

Processing and analysis of cardiac optical mapping data obtained with potentiometric dyes.

Optical mapping has become an increasingly important tool to study cardiac electrophysiology in the past 20 years. Multiple methods are used to process and analyze cardiac optical mapping data, and no consensus currently exists regarding the optimum methods. The specific methods chosen to process optical mapping data are important because inappropriate data processing can affect the content of ...

Optical imaging of voltage and calcium in cardiac cells & tissues.

Cardiac optical mapping has proven to be a powerful technology for studying cardiovascular function and disease. The development and scientific impact of this methodology are well-documented. Because of its relevance in cardiac research, this imaging technology advances at a rapid pace. Here, we review technological and scientific developments during the past several years and look toward the f...